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General Information

Full Name John Christopher Janetzko

Education

  • 2011-2017
    Ph.D. in Chemistry
    Harvard University, Cambridge, MA, USA
  • 2007-2011
    Honours B.Sc. in Chemistry
    University of Toronto, Toronto, ON, Canada
    • Graduated with high distinction

Experience

  • 2022 - present
    Instructor in Molecular & Cellular Physiology
    Stanford University, Stanford, CA, USA
  • 2017-2022
    Postdoctoral Fellow in GPCR structure and biophysics
    Stanford University, Stanford, CA, USA
    • Research with Dr. Brian Kobilka
    • Major research accomplishments
      • Part of a team that obtained a molecular structure of the Neurotensin type 1 receptor (NTSR1) in complex with β-arrestin 1 by single particle cryo-electron microscopy (cryo-EM).
      • Established a mechanistic basis for phosphoinositide regulation of β-arrestin function.
      • Used single-molecule FRET spectroscopy (smFRET) to investigate the mechanism of β-arrestin activation, and GPCR-β-arrestin complex dynamics.
    • Relevant skills
      • bulk and single-molecule fluorescence spectroscopy
      • cryo-EM and model building
      • proteomics and structural mass spectrometry
      • membrane protein biochemistry
      • cellular proximity assays
      • pharmacology
      • data visualization in R
  • 2011-2017
    Graduate student in chemistry and chemical biology
    Harvard University, Cambridge, MA, USA
  • 2008-2011
    Undergraduate researcher in organic synthesis
    University of Toronto, Toronto, ON, Canada
    • research with Dr. Robert A. Batey
  • 2007-2008
    Undergraduate researcher in organometallic chemistry
    University of Toronto, Toronto, ON, Canada
    • research with Dr. Datong Song

Honors and Awards

  • 2022
    • National Institutes of Health (NIH), National Institute of General Medical Science (NIGMS), K99/R00 Pathway to Independence Award (Stanford)
  • 2018
    • Damon Runyon Cancer Research Foundation Postdoctoral Fellowship (Stanford)
    • American Heart Association Postdoctoral Fellowship (declined)
    • Stanford School of Medicine Dean's Postdoctoral Fellowship (Stanford)
  • 2016
    • Christensen Travel Prize for Outstanding Research Achievement (Harvard)
  • 2013
    • Derek Bok Center Certificate of Distinction in Teaching (Harvard)
    • Natural Sciences and Engineering Research Council of Canada (NSERC) Postgraduate Scholarship PGS-D3 (Harvard)
  • 2012
    • Derek Bok Center Certificate of Distinction in Teaching (Harvard)
    • Natural Sciences and Engineering Research Council of Canada (NSERC) Postgraduate Scholarship PGS-M (Harvard)
  • 2011
    • Harold Willett Stewart Memorial Scholarship (UofT)
    • The University of Toronto Chemistry Club Prize in Chemistry (UofT)
  • 2010
    • The Sarah C. Gollop and William G. Gollop Memorial Scholarship in Chemistry (UofT)
    • The Ivan Szak Scholarship in Chemistry (UofT)
    • The David McLaren Scholarship in Chemistry (UofT)
    • The Canadian Society for Chemistry Silver Academic Medal (UofT)